Gastric carcinoma, diffuse type (mucinous)

Gastric adenocarcinoma is a malignant epithelial tumor, originating from glandular epithelium of the gastric mucosa. According to Lauren classification, gastric adenocarcinoma may be: intestinal type, diffuse type and mixed type.

Gastric carcinoma diffuse type mucinous

Gastric adenocarcinoma, diffuse (infiltrative) type. Tumor cells are discohesive and secrete mucus which is delivered in the interstitium producing large pools of mucus/colloid (optically "empty" spaces) - mucinous (colloid) adenocarcinoma, poorly differentiated (Lauren classification). If the mucus remains inside the tumor cell, it pushes the nucleus against the cell membrane - "signet-ring cell". (H&E, ob. x10)



Gastric carcinoma, diffuse type (mucinous) - detail
Gastric carcinoma diffuse type mucinous (detail)

Gastric adenocarcinoma, diffuse type. (H&E, ob. X20)

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Last updated : 01/30/2009