Invasive ductal carcinoma of the breast

Invasive ductal carcinoma of the breast

Invasive (infiltrating) ductal carcinoma of the breast is a malignant epithelial tumor resulted from proliferation of ductal epithelium of breast. It is the most common type of breast cancer (70 - 80 %). Atypical tumor cells form ribbons, tubules or nests, broke the basement membrane of the duct and infiltrate the surrounding tissues (fat tissue - photo, skeletal muscle and/or skin). Tumor cells induce desmoplastic reaction in stroma (abundant fibrosis, collagen). (H&E, ob. x20)

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Last updated : 01/30/2009