Poorly differentiated hepatocellular carcinoma

Poorly differentiated hepatocellular carcinoma

Hepatocellular carcinoma, poorly differentiated (photo - upper right), developed on liver cirrhosis. This malignant epithelial tumor consists in tumor cells, discohesive, pleomorphic, anaplastic, giant. The tumor has a scant stroma and central necrosis because of the poor vascularization. In well differentiated forms, tumor cells resemble hepatocytes, form cords and nests, and may contain bile pigment in cytoplasm. (H&E, ob. x20)

Poorly differentiated hepatocellular carcinoma (detail)

Poorly differentiated hepatocellular carcinoma. (H&E, ob. x20)

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Last updated : 01/30/2009