Simple typical hyperplasia of endometrium
Endometrial hyperplasia (hyperplasia of endometrium) is a dishormonal lesion, produced by hyperestrinism, which generates the glandular and stromal proliferation of endometrium. It may be simple or complex, typical or atypical. Endometrial hyperplasia may regress or may transform into adenocarcinoma. Simple, typical hyperplasia has a low risk of malignancy (less than 1 %), while the risk for complex, atypical hyperplasia is about 25 %.
Simple, typical hyperplasia of endometrium. The hyperplastic endometrium consists in proliferated epithelium with quasi-normal appearing (stratified, tall columnar, or cuboidal) and proliferated cells in stroma. Often, the glands are dilated (cystic "Swiss cheese" hyperplasia). (H&E, ob. x10)
Simple typical hyperplasia of endometrium (detail)
Simple, typical hyperplasia of endometrium. (H&E, ob. x20)